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Ronald Koeman's men travel to Wales in fine form, following on their crushing 3-1 and 4-0 defeats over West Ham and Newcastle respectively.
Swansea have also had an impressive start to season, with their 100% Premier League record only coming to an end last week after succumbing to a spirited loss away at title favourites Chelsea. With ex-Saints player Garry Monk at the helm, Swansea still have a 100% home record in tact for both league and cup games.
Southampton won their first game away at Swansea in over 50 years last season, managing to scrape a 1-0 win at the Liberty Stadium last season, with a late Rickie Lambert winner after he bundled the ball into the net.
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Sadio Mané will not be featuring as he only arrived in England yesterday, following on from his international duty with Senegal. The pacy attacker's arrival was a little too late for him to be in contention for today's game, so he remains the sole summer signing to have not made their Saints debut.
Ahead of this fixture, there are no real injury concerns for Southampton other than Jay Rodriguez, who remains sidelined as he nurses his knee injury back to health. Swansea will be without Leon Britton and Jordi Amat.
Another ex-Saint to be involved in today's game is nippy Swansea winger Nathan Dyer. Dyer had mixed fortunes during his time on the south coast. He rose through the Hampshire club's youth ranks and showed flashes of brilliance as well as, at times, being one of the more frustrating figures on the St. Mary's pitch.
His time at Southampton culminated when he, along with Bradley Wright-Phillips, were caught stealing handbags from a Portsmouth nightclub. He was later released on a free after not having his contract extended.