Southampton are presently on an impressive run of three Premier League away wins on the bounce and will want to continue this rich vein of on-the-road form against a QPR side languishing in the relegation zone.
Saints' startling six-game unbeaten run came to a sudden halt on Sunday as Swansea's Jonjo Shelvey delivered a sucker punch blow to Southampton's flailing Champions League dreams, meaning the South Wales side left St. Mary's with the spoils.
QPR haven't won a game since December in a seven-game run without victory. However, with Tuesday's departure of Rangers manager/Saints villain Harry Redknapp, caretaker bosses Kevin Bond and Chris Ramsey will be aiming to put a stop to that.
Morgan Schneiderlin and Victor Wanyama are rumoured to be in the frame to feature today, while Saints' deadline day signing Filip Djuričić is not available to play due to some work permit issues.
Much has been made of QPR's poor away form, which has seen them not pick up a single point away from Loftus Road this season. However, their home form is impressive with a record of five wins, four draws and only three defeats in their West London home. Charlie Austin also has a habit of scoring against the Saints, so watch out for that one.
St. Mary's Musings prediction: QPR 1-2 Southampton