Date/time: 26/10/2016, 19:45 (UK), 14:45 ET, 11:45 PT (USA)
Venue: St. Mary's Stadium, Southampton, UK
Official: Chris Kavanagh
TV: None (UK), check out LiveSoccerTV for alternatives.
Streaming: None (UK)
Radio: BBC Radio Solent (UK)
While Southampton are hitting their stride in the Premier League, Sunderland continue to languish at the foot of the league table. However, the two teams played to a draw at St. Mary's this season, with Saints arguably lucky to escape with a point through a late equaliser.
Saints boss Claude Puel will be missing Shane Long, Ryan Bertrand, Matt Targett and Cedric Soares through injury. Meanwhile, David Moyes' Sunderland are expected to be missing Patrick van Aanholt and Jack Rodwell with injuries.
Sunderland reached the final back in 2014, losing 3-1 to Premier League giants Manchester City. That run helped inspire the Black Cats to improbably avoid relegation from the league in the 2013/14 campaign and Moyes will be hoping similar success can inspire his side this time around.
Sunderland equalled their record defeat at Southampton in 2014, losing 8-0. They have lost to Sheffield Wednesday, West Ham and Watford by the same margin since being formed in 1879.
That scoreline is the only time in the past 16 meetings between the clubs that a victory has been achieved by more than a single goal.
Sunderland are the only team in the top five leagues in England yet to win a game.
Southampton have conceded just three goals in nine matches.
Bet 365: Southampton: 4/9 - Draw: 15/4 - Sunderland: 15/2
Bet Victor: Southampton: 4/9 - Draw: 7/2 - Sunderland: 15/2