Date/time: 15/05/2016, 15:00 (UK) - 10:00 ET, 07:00 PT (USA)
Venue: St. Mary's Stadium, Southampton, UK
TV: None (UK), E! (USA)
Streaming: None (UK) , NBCSN (USA)
Radio: BBC Radio Solent (UK)
Southampton and coach Ronald Koeman will be hoping to end the season on a high and secure their spot to compete in the UEFA Europa League qualifying or group stages for the upcoming 2016/17 campaign.
Saints will be missing Jordy Clasie according to Koeman in his latest press conference, but will welcome back Sadio Mane who sat out Saints' impressive 2-1 victory away at Tottenham Hotspur.
Crystal Palace have other things on their mind as they will be heading to Wembley in the FA Cup final against Manchester United next weekend, so it's widely thought the South Londoners will be resting a few key names with nothing to play for in the week.
This school of thought may be justified as the Eagles lost Joe Ledley after he had suffered a fractured leg against Stoke City last weekend. Yohan Cabaye and Wilfried Zaha are also expected to be injury doubts for Sunday's game.
Palace earned their first ever Premier League win over Southampton in their 1-0 victory at Selhurst Park earlier in December. It took 13 attempts to do so!
In fact, three of the last four meetings between the two sides have ended in 1-0 scorelines.
Ronald Koeman's men have won their last three Premier League games. But, they haven't won four in a row all season. At home, Saints have won seven and lost just one match in their last nine league games at St. Mary's.
Saints winger Dusan Tadic has been involved in eight goals in his last four Premier League appearances - scoring two and assisting six.
Palace, however, haven't won away from home in the league since December, drawing five and losing five.
They have scored the highest percentage of goals from set pieces in the league this season, though! 47% of their goals have come from set plays. They're equally adept at defending them too - conceding the lowest percentage of goals from set pieces in the league at 21%.
Bet Victor: Southampton: 3/10 - Draw: 9/2 - Crystal Palace: 9/1
Bet 365: Southampton: 1/3 - Draw: 19/4 - Crystal Palace: 9/1