Date/time: 07/05/2017, 13:30 (UK), 08:30 ET, 05:30 PT (USA)
Venue: Anfield, Liverpool, UK
Streaming: SkyGo (UK), NBCSN (USA)
Radio: BBC Radio Solent (UK)
With boos ringing round St. Mary's at half-time, full-time and for things as simple as substitutions, it's imperative Southampton boss Claude Puel gets a positive result at Anfield this week as his Saints side takes on Jurgen Klopp's Liverpool, who are feeling the pressure as they battle to earn Champions League football for next season.
The two sides have already played each other three times this season, with two 1-0 wins going in Saints' favour in the two-legged EFL Cup semi-final and a 0-0 draw between the pair at St. Mary's earlier in the 2016/17 Premier League campaign. Saints haven't conceded in all three games.
Saints striker Charlie Austin could be available for the first time since dislocating his shoulder in December, having made his comeback for the club's U23 side on Friday night.
Liverpool's Philippe Coutinho is a doubt to feature, though he is confident he will be fit in time despite picking up a dead leg in his team's 1-0 win over Watford on Monday. If he isn't available, former Saint Adam Lallana is expected to deputise.
Stats Zone (via BBC Sport):
Liverpool are yet to score against Southampton in three games this season, drawing 0-0 in the Premier League in November and losing 1-0 in both legs of the EFL Cup semi-final.
The Reds have also failed to beat Southampton in all three league meetings since Jurgen Klopp became their manager (D2, L1).
However, Southampton's only Premier League win in their last five visits to Anfield came in September 2013 courtesy of a goal from Dejan Lovren, now at Liverpool (D1, L3).
They have earned 20 points from their last nine matches (W6, D2, L1), second only to Tottenham over the same period.
Nonetheless, they are in danger of recording successive league defeats at Anfield for the first time since September 2012.
Jurgen Klopp has an identical record to predecessor Brendan Rodgers after 65 league games in charge of Liverpool: W33, D18, L14.
There have been a league-high 208 goals scored in those 65 matches under the German, an average of 3.2 per game.
Liverpool have scored 16 Premier League goals in the 15 minutes before half-time this season, more than any other side.
Klopp could, for the first time, name the same Liverpool starting XI for a fourth successive Premier League game.
Claude Puel's side have only taken two points from nine games this season against sides in the top six prior to the weekend fixtures (D2, L7).
Saints have won three of their last five Premier League away games, following a run of only two victories in 12.
Seven of Southampton's 11 Premier League wins in 2016-17 have come on a Sunday.
They must win their remaining five matches to avoid finishing the season with their lowest points tally in four years.
Manolo Gabbiadini scored four goals in his first three Premier League appearances but has subsequently failed to score in four games, managing just one shot on target.
Claude Puel is unbeaten in all five competitive matches as a manager against Liverpool (W3, D2).
Bet 365: Liverpool: 3/5 - Draw: 16/5 - Southampton: 5/1
Bet Victor: Liverpool: 8/13 - Draw: 16/5 - Southampton: 5/1
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